The kidneys play a crucial role in bone formation and overall bone health due to their involvement in several key processes that regulate calcium, phosphate, and vitamin D metabolism.
The kidneys are responsible for the final activation of vitamin D, which is essential for calcium absorption in the intestines.
The kidneys help maintain the balance of calcium and phosphate in the blood, which is essential for bone mineralization. Bone formation requires a proper balance of both minerals.
The kidneys work with the parathyroid glands to regulate calcium levels through the secretion of parathyroid hormone (PTH).
can disrupt the kidneys' ability to regulate calcium, phosphate, and vitamin D metabolism, leading to renal osteodystrophy-a condition characterized by weakened bones.